Z51.81 Encounter for therapeutic drug level monitoring
ICD-10-CM · CMS code reference
Official ICD-10-CM description: Encounter for therapeutic drug level monitoring
Coding notes
From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.
Excludes1
Not coded together with this code. The exception is when the two conditions are unrelated to each other.
- encounter for blood-drug test for administrative or medicolegal reasons (Z02.83)
- holiday relief care (Z75.5)
- follow-up examination after treatment (Z08-Z09)
Excludes2
Not part of this code, but both can be coded when both are documented.
- follow-up examination for medical surveillance after treatment (Z08-Z09)
Code also
A second code may be needed. Sequencing depends on the encounter.
- any long-term (current) drug therapy (Z79.-)
- condition requiring care
Related codes
Z51.0Encounter for antineoplastic radiation therapy ICD-10-CMZ51.11Encounter for antineoplastic chemotherapy ICD-10-CMZ51.12Encounter for antineoplastic immunotherapy ICD-10-CMZ51.5Encounter for palliative care ICD-10-CMZ51.6Encounter for desensitization to allergens ICD-10-CMZ51.89Encounter for other specified aftercare ICD-10-CMZ51.AEncounter for sepsis aftercare ICD-10-CM
Common questions
Is Z51.81 a billable code?
Yes. Z51.81 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.